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Publications

Manuscript submitted :​

  • Nia CC, Yu CS, Wei SY, Dai JZ, Chang CL, Ting HC, Chang CY*, Chen YC*. Light-Tunable Micropatterned Gelatin Hydrogels Enable Spatially Organized 3D Human Neuromuscular Junctions for Disease Modeling and In Vivo Vascularization. (Submitted)​

  • Tsai MC, Zhang SL, Wei SY, Chen KC, Cheng YT, Chang CL, Ting HC, Chang CY, Jeng US, Lu TT, Chen YC. Light-Programmable Gelatin Hydrogels for Reversible Stiffness Modulation and Phase-Specific Tissue Regeneration. (Submitted)

​Articles:

2026

  • Chang CY*, Chiang CY, Ting HC, Tsai YJ, Chan PC, Chen MF, Guo YT, Liu YH, Chen YS, Chuang CH, Lin PC, Chuang LH, Huang MH, Tung YC, Chen PY, Harn HJ, Su HL* and Lin SZ*. Cryopreservable Dopaminergic Progenitors Derived from Human iPSCs with Accelerated Loss of Pluripotency and Early Functional Restoration in Parkinsonian Rats. npj Parkinson's Disease, (2026). https://doi.org/10.1038/s41531-026-01399-4. (SCI, R/C=20/330, IF=8.5, NEUROSCIENCES). First & Corresponding author

​2025

  • Ting HC, Guo YT, Su HL, Chen YS, Lin SZ, Harn HJ, Chang CY*. Rapid iPSC-Derived Neuromuscular Junction Model Uncovers Motor Neuron Dominance in Amyotrophic Lateral Sclerosis Cytopathy. Cell Death Discov, 11, 23 (2025). https://doi.org/10.1038/s41420-025-02302-5. (SCI, R/C=42/204, IF=7.1, CELL BIOLOGY). Corresponding author

2024

  • Deng YC, Liu JW, Ting HC, Kuo TC,Chiang CH, Lin EY, Harn HY, Lin SZ, Chang CY*, Chiou TW*. n-Butylidenephthalide Recovered Calcium Homeostasis to Ameliorate Neurodegeneration of Motor Neurons Derived from Amyotrophic Lateral Sclerosis iPSCs. PLoS One 19, e0311573 (2024). https://doi.org/10.1371/journal.pone.0311573. (SCI, R/C=31/134, IF=2.9, MULTIDISCIPLINARY SCIENCES). Corresponding author

2022

  • Wu SF, Lin CY, Tsai RK, Wen YT, Lin FH, Chang CY, Shen CI, Lin SZ, Harn HJ, Chiou TW, Liu CS, Chen YT, Su HL. Mitochondrial Transplantation Moderately Ameliorates Retinal Degeneration in Royal College of Surgeons Rats. Biomedicines 2022; 10(11), 2883. (SCI, R/C=69/277, IF=4.7, PHARMACOLOGY & PHARMACY).

  • Ting HC, Su HL, Chen MF, Harn HJ, Lin SZ, Chiou TW, Chang CY*. Robust Generation of Ready-to-Use Cryopreserved Motor Neurons from Human Pluripotent Stem Cells for Disease Modeling. International journal of molecular sciences 2022; 23(21),13462. (SCI, R/C=69/297, IF=6.208, BIOCHEMISTRY & MOLECULAR BIOLOGY). Corresponding author

2021

  • Ting HC, Yang HI, Harn HJ, Chiu IM, Su HL, Li X, Chen MF, Ho TJ, Liu CA, Tsai YJ, Chiou TW, Lin SZ, Chang CY*. Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons. Cells 2021; 10(10), 2773. (SCI, R/C=51/195, IF=7.666, CELL BIOLOGY). Corresponding author

  • Chang CY*, Ting HC, Liu CA, Su HL, Chiou TW, Harn HJ, Lin SZ and Ho TJ. Differentiation of Human Pluripotent Stem Cells into Specific Neural Lineages. Cell Transplant 2021:30:9636897211017829. (SCI, R/C=9/25, IF=4.139, TRANSPLANTATION). First author

2020

  • Chang CY*, Ting HC, Liu CA, Su HL, Chiou TW, Lin SZ, Harn HJ, Ho TJ. Induced Pluripotent Stem Cell (iPSC)-Based Neurodegenerative Disease Models for Phenotype Recapitulation and Drug Screening. Molecules 2020;25(8). (SCI, R/C=65/179, IF=4.927, CHEMISTRY, MULTIDISCIPLINARY). First author

2019

  • Yu SJ, Wang YC, Chang CY, Hsieh W, Chen S, Yang CS, Lin SZ, Wang Y. NanoCsA improves the survival of human iPSC transplant in hemiparkinsonian rats. Brain Res 2019;1719:124-132. (SCI, R/C=156/275, IF=3.61, NEUROSCIENCES)

  • Lin CY, Wu CL, Lee KZ, Chen YJ, Zhang PH, Chang CY, Harn HJ, Lin SZ, Tsai HJ. Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA. Elife 2019;8. (SCI, R/C=8/94, IF=8.713, BIOLOGY)

2018

  • Chang CY*, Ting HC, Liu CA, Su HL, Chiou TW, Harn HJ, Lin SZ. Induced pluripotent stem cells (iPSCs): A powerful neurodegenerative disease modeling tool for mechanism study and drug discovery. Cell Transplantation. 2018;27(11):1588-1602. (SCI, R/C=9/25, IF=4.139, TRANSPLANTATION). First author

  • Liu CA, Chang CY, Hsueh KW, Su HL, Chiou TW, Lin SZ, Harn HJ. Migration/invasion of malignant gliomas and implications for therapeutic treatment. International journal of molecular sciences. 2018. 19(4). (SCI, R/C=54/166, IF=3.226, CHEMISTRY, MULTIDISCIPLINARY)

  • Ting HC#, Chang CY#, Lu KY, Chuang HM, Tsai SF, Huang MH, Liu CA, Lin SZ, Harn HJ. Targeting cellular stress mechanisms and metabolic homeostasis by chinese herbal drugs for neuroprotection. Molecules. 2018. 23(2). (SCI, R/C=17/59, IF=2.861, CHEMISTRY, ORGANIC). First author

2017

  • Chang CY*, Ting HC, Su HL, Jeng JR. Combining Induced Pluripotent Stem Cells and Genome Editing Technologies for Clinical Applications. Cell Transplantation. 2017. (SCI, R/C=14/38, IF=3.01, TRANSPLANTATION). First author

2015

  • Chang CY*, Chen SM, Lu HE, Lai SM, Lai PS, Shen PW, Chen PY, Shen CI, Harn HJ, Lin SZ, Hwang SM, Su HL. N-butylidenephthalide attenuates Alzheimer's disease-like cytopathy in Down syndrome induced pluripotent stem cell-derived neurons. Scientific Reports. 2015, 5:8744. (SCI, R/C=7/63, IF=5.47, MULTIDISCIPLINARY SCIENCES). First author

  • Chen SM, Lee MS, Chang CY, Lin SZ, Cheng EH, Liu YH, Pan HC, Lee HC, Su HL. Prerequisite OCT4 Maintenance Potentiates the Neural Induction of Differentiating Human Embryonic Stem Cells and Induced Pluripotent Stem Cells. Cell Transplantation. 2015;24(5):829-44. (SCI, R/C=34/124, IF=3.427, MEDICINE, RESEARCH & EXPERIMENTAL)

2014

  • Shen SC, Shen CI, Lin H, Chen CJ, Chang CY, Chen SM, Lee HC, Lai PS, Su HL. Susceptibility of human embryonic stem cell-derived neural cells to Japanese encephalitis virus infection. PLoS One. 2014 Dec 17;9(12):e114990. (SCI, R/C=11/63, IF=3.057, MULTIDISCIPLINARY SCIENCES)

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